Molecular Masterpieces: Crafting Genetics with CRISPR MiniLab (M3019)


Simulate CRISPR-Cas9 action and DNA repair mechanisms to edit genomes using a paper model. Perform gel electrophoresis to demonstrate evidence of gene editing.


Call us at (858) 684-3190 or contact us for more information on ordering.

Out of stock

SKU: M3019 Category: Tags: ,


In this hands-on lab, students will delve into the history of CRISPR by exploring the inner workings of CRISPR-Cas9 complex in prokaryotes by designing their own synthetic guide RNA (sgRNA) and simulating the action of CRISPR-Cas9 in recognizing and cutting a DNA sequence at its complementary site. Then, students compare and contrast the DNA repair mechanisms in eukaryotes and discover how these can be harnessed, along with CRISPR-Cas9 technology, to precisely knock-out or knock-in genes of interest in eukaryotes. Finally, gel electrophoresis is used to demonstrate the successful CRISPR-Cas9 cleavage or insertion of a target gene sequence.

Check out the videos below for more on CRISPR!

Materials Included in each MiniLab

Each MiniLab contains enough materials for 10 workstations, 2 – 3 students per workstation.

Materials include:

  • Four Ready-to-Load DNA samples
  • MiniOne® Universal Marker
  • Ten 1% agarose GreenGel™ GelCups
  • Two 50 mL BufferCups Tris-Borate-EDTA (TBE) buffer concentrate
  • One bag of 0.65 mL microcentrifuge tubes
  • One bag of 2 – 200 µL micropipette tips
  • 10 sets of activity cards

Additional information

Weight 1.2 lbs
Dimensions 10 × 5.5 × 4.5 in

Supporting Documents


You may also like…

  • MiniOne Classroom Package of 10 (M1010)

    $2,999.00 M1010
  • The MiniOne System (M1000)

    $334.00 M1000